ORF or Orf may refer to:

• Norfolk International Airport, IATA airport code ORF
• Observer Research Foundation, an Indian research institute
• One Race Films, a film production company founded by Vin Diesel
• Open reading frame, a portion of the genome that has the potential to code for a protein
• Open Road Films, a joint venture of Regal Entertainment Group and AMC Theatres
• Operation River Falcon, a military operation in the Iraq War
• Operation Royal Flush, a military deception employed by the Allied Nations during the Second World War
• ORF (broadcaster), Austrian public service broadcaster
• Orf (disease), a cutaneous condition
• ORF format, Olympus raw image file format with extension .orf
• Orf, Iran, a village in Kohgiluyeh and Boyer-Ahmad Province, Iran